Trouble has beset Joseph’s brothers as Simeon is detained. Jacob’s Trouble will follow the “rapture” of the Church – Israel’s troubles.
Genesis 42:21-22 21 And they said one to another, we are verily guilty concerning our brother, in that we saw the anguish of his soul, when he besought us, and we would not hear: therefore is this distress come upon us. 22 And Reuben answered them saying, spake I not unto you saying, do not sin against the child: and ye would not hear? Therefore, behold, also his blood is required.
Genesis 42:36 And Jacob their father said unto them, me have ye bereaved of my children: Joseph is not, and Simeon is not, and ye will take Benjamin away: all these things are against me.
Jeremiah 30:7 Alas!, for that day is great, so that none is like it, it is even the time of Jacob’s trouble; but he shall be saved out of it.